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Newsletter  
CEO Spotlight: Andrew Heath, Protherics, Inc.  
By Sterling-Hoffman Life Sciences Journal

When he hires, he says he just doesn’t go by the resume of the person; attitude, style and personality are also high on the list. Having been close to sickness and human suffering through his work as a practicing physician, he was inspired to contribute to medicinal drug development. Andrew Heath, CEO, Protherics, Inc. talks to Sterling-Hoffman Life Sciences Journal about his company’s successes, future opportunities and the challenges faced by the industry today.

Sterling-Hoffman Life Sciences Journal (SHSLJ): What is your greatest source of inspiration in the life sciences industry? And in your life?
Andrew Heath (AH): Being so close to sickness and human suffering as a practicing physician inspired me to make a contribution in another way – marrying my business skills and medical experience to develop drugs. I can't imagine a more fulfilling and rewarding combination.

SHSLJ: What would you be doing if you weren't working in the life sciences industry?
AH: There are several sectors that maybe aren't as rewarding, but sure a lot of fun – fashion, property…

SHSLJ: How do you like to spend your time when not at work?
AH: I have a house near Bordeaux, so wine is always high on the list.

SHSLJ: When did you know that you wanted to work in the life sciences industry?
AH: As a child I always wanted to be a doctor – and once qualified, got more and more involved in clinical trials.

SHSLJ: Which segment within the life sciences industry do you see as a growing prospect in the coming years?
AH: Biotech will continue to replace big pharma's in-house R&D as the major innovator and source for new therapeutics.

SHSLJ: Can you share one or two of your company's most exciting successes?
AH: Our first FDA approval – CroFab (for rattlesnake bites) in 2000, and our deal with AstraZeneca with our anti-TNF antibody for sepsis in December 2005.

SHSLJ: What are the challenges that still need to be overcome within the bio-pharmaceutical industry?
AH: Protecting intellectual property rights have become more important than ever, if we are to maintain an appetite to invest in programs with a 10 –15 year horizon. We also need regulators to better understand, in the interest of the patient, the financial implications of the decisions taken.

SHSLJ: What are the advantages of working at your company?
AH: We are small, but not too small, we are serious, but have fun, and we know that what we do impacts people's lives.

SHSLJ: Where do you think you have outsmarted your competitors?
AH: We have stuck with a technology base (polyclonal antibodies) and an indication (sepsis) because we believe we can resolve a significant unmet medical need. It's great to prove the skeptics wrong and we're already well on the way.

SHSLJ: How do you want to position the company in the next 5 years?

AH: We need to continue to grow both organically and through M&A. In 5 years we expect to have at least two or three new products from our own pipeline on the market, and sell through our own Marketing and Sales Teams.

SHSLJ: In your opinion, what is the value of education in today's generation as compared to yours?
AH: With a growing gap between rich and poor in most countries, education is more important than ever as a route to facilitate change – be it in one's own life or those of others.

SHSLJ: Tell me about your core initiatives right now - what are some of the focus areas for 2008?
AH: We now have 6 programs in Phase 2. We must ensure that we deliver results on time and to budget.

SHSLJ: How do you hire the best people? What are the top 3 things you look for when hiring?
AH: Someone once said that you make a hire on a resume, but fire on personality. You must look beyond the resume at the intangibles – attitude, style and personality.

SHSLJ: Is finding life sciences professionals a challenge?
AH: Finding good people is hard whatever sector you work in. You can start by finding a good recruiter.

SHSLJ: What trends do you see in the life sciences industry and what opportunities are in store for your company?
AH: Despite the current investor bias away from biotech, the long-term outlook is excellent, with biotech R&D the overwhelming source of innovative medicines.



Andrew Heath is CEO of Protherics, Inc., a leading biopharmaceutical company focused on developing, manufacturing and marketing critical care and cancer products. He holds an M.D. and Ph. D. from Sweden’s Gothenburg University. After a career in research and clinical medicine at Vanderbilt University, Dr. Heath joined the pharmaceutical industry in 1989. He has held both R&D and commercial positions with Glaxo and Astra, in Europe and the US. Dr. Heath served as Chief Executive Officer at AeroGen Inc, from 1996, joining Therapeutic Antibodies as Chief Executive Officer in March, 1998. He continued as CEO upon the formation of Protherics in 1999. He is a Non-Executive Director of XLTG Inc. For interview feedback, contact Dr. Heath at andrew.heath@protherics.com