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Newsletter  
CEO Spotlight: Vamsi Maddipatla, LAXAI Inc.  
By Sterling-Hoffman Life Sciences Journal

For him, offshore outsourcing related to R&D is the key to accessing talent and getting to the market fast precedes cost savings (in that order). His vision for the life sciences industry is affordable drugs for everybody, even those without health insurance. Vamsi Maddipatla, CEO of LAXAI Inc, discusses with Sterling-Hoffman Life Sciences Journal on why he chose the recession-proof health sector to work in, his motivation behind founding LAXAI and the top three things he looks for when hiring people to work for him.

Sterling-Hoffman Life Sciences Journal: Who is your greatest source of inspiration in the life sciences industry? And in your life?
Vamsi Maddipatla: My work experience in Pfizer and J&J as a Management Consultant was the inspiration to start a company to provide services in the life sciences industry. My greatest inspiration in life is Richard Branson.

SHLSJ: What would you be doing if you weren’t working in the Life Sciences Industry?
VM: I would probably have started a company in the healthcare sector. I believe in being in, or playing in a recession-proof industry. I have a great desire to play a role in transforming the healthcare system.

SHLSJ: Who were your role models when you joined the industry?
VM: Richard Branson

SHLSJ: What changes have you noticed in yourself from when you started the company to today?
VM: I have become patient and have a natural shock absorber to deal with the dynamics of running a company. Time has become very valuable and I can appreciate every minute of the time I spend with my family and business. I can run a business more efficiently and have got a lot of experience in managing people. Business has become a game to play carefully, which paves the way and gives you access to many more opportunities to create employment and service a need.

SHLSJ: What motivated you to found LAXAI?
VM: I always wanted to be associated with drug discovery and development, which is very critical to bringing new drugs to market and is indirectly critical to improve the quality of life as well as to save lives. I wanted to exploit my roots in India as well as experience as a management consultant and presence in the USA to provide services in two critical phases (discovery & development) in the drug R&D. There are immediate and pressing needs to bring new drugs to the market, at the same time reduce the costs involved in doing so. This was a perfect opportunity to go after and I did so by providing clinical data management bio-statistics services and contract research drug development services with our labs in India.

SHLSJ: What are the benefits of moving R&D offshore?
VM: There are a lot of benefits in moving R&D offshore to countries like India. Often the work ‘offshore outsourcing’ is directly mapped to the term ‘cheap labor and cost savings.’ The case for R&D is very different. The major benefit of R&D outsourcing offshore is the access to talent. The second benefit to biopharma companies is reduced time to market i.e., more molecules can be screened and developed and brought through CMC section much faster. The third benefit is cost savings.

SHLSJ: What are the challenges that still need to be overcome with offshore R&D?
VM: Not all areas in R&D can be outsourced even today. There are competencies that do not exist with service providers offshore. The other major challenge is protection of intellectual property. Other challenges that exist are accountability, transparency and efficient project management. With R&D outsourcing increasing, it will reach a maturity level that will overcome these challenges.

SHLSJ: Are more North American companies moving their research overseas these days? Does this help accelerate the discoveries being made in the Life Sciences industry?
VM: YES! 80% of the top 50 biopharma (companies) are outsourcing R&D though it may be a very small component. Some companies have taken a strategic decision to adopt R&D outsourcing as a corporate strategy and some companies are exploring this with pilot projects and a few companies have a presence in countries like India to manage the R&D efforts in the respective countries. This definitely helps companies bring more molecules to clinical faster with lesser costs that directly increases the hit ratio of molecules in less time.

SHLSJ: Where do you think you have outsmarted your competitors?
VM: I don’t think we have outsmarted our competitors, but our positioning and business model differentiates us. We are providing services to address the capacity shortages and bottlenecks in the drug R&D lifecycle with a global delivery model.

We are local and also offshore with capabilities in both discovery and clinical research. We are perfectly positioned with the right services whereby biopharma companies can work with a local company to ensure that we are accountable as well as realize the cost savings of an offshore company utilizing our delivery in India. We are well positioned to exploit the tremendous R&D spending both in the US and offshore in India.

SHLSJ: What part does the life sciences industry play to improve the society?
VM: Life science companies play a very vital role in improving the quality of life and also in saving life. Without these companies, the average life span would not have increased from 47 in 1900, to 70 – 80 years currently. However the cost of these drugs needs to come down and they need to be affordable to common people without health insurance.

SHLSJ: What initiatives is Laxai taking to address these issues?
VM: We at LAXAI want to play a role in conducting R&D and clinical research in the most cost-effective manner working with biopharma companies, whereby affordable drugs can be released in the market.

SHLSJ: Tell me about your core initiatives right now – what are some of the focus areas for 2008?
VM: We are expanding our presence to more locations in the US to include NC, MA and CA. We want to work with biopharma companies whereby we provide them with a local presence and create captive R&D teams and facilities in India. Our major focus areas in 2008 are medicinal and process chemistry, clinical research supported with end-to-end clinical data management and Biostatistics.

SHLSJ: What kind of people can make the best CEOs in this industry?
VM: CEOs with a passion to contribute to quality work can only succeed. CEOs with a vision and patience in the industry can succeed. This industry is capital intensive and quality driven. CEOs in this industry need to believe in this.

SHLSJ: How do you hire the best people? What are the top 3 things you look for when hiring?
VM: We invest in creating an organization and culture that attracts and retains people. Once a talented person joins our company we give no chance for the person to be unhappy.

We look for proven experience, leadership, creativity and a commitment to succeed. If we hire people with these qualities, the company is bound to succeed. I believe that if the company is positioned well to capture the opportunity with the right business model, then the right people are the formula for success.

SHLSJ: Is finding life sciences professionals a challenge?
VM: Experienced life sciences (professionals) are hard to find, but creative and experienced professionals are a tough find.

SHLSJ: What trends do you see in the life sciences industry and what opportunities are in store for your company?
VM: R&D outsourcing is bound to increase by many folds, which we perceive as a great opportunity, as we are well geared up. Another major opportunity is the need for companies to submit clinical data to the FDA that is CDISC compliant. This is going to drive biopharma companies to adopt clinical data management and electronic data capture, which again is one of our major service areas today.



Vamsi Maddipatla is Founder and CEO of LAXAI, a leading provider of drug research and development services with blended-shore sourcing and clinical data management services for the life sciences industry across Americas, Europe and Asia. Throughout his career, he has demonstrated success in both strategic development and key operations roles. Vamsi has developed and expanded the capability and capacity of sales and marketing teams, strategic market research and business analysis divisions, and business development departments. He has been responsible for planning activities in leading life sciences organizations to realize financial and operational returns on investment. Vamsi has worked as a Management Consultant with a focus on enterprise technology planning, providing services to Deloitte & Touche, Pfizer, Johnson & Johnson and Merrill Lynch on selecting and implementing business processes to increase customer profitability. He holds a Bachelor of Science degree in Electronics and Instrumentation and Master’s degree in Computer Science from Fairleigh Dickinson University. Vamsi is also the Founder of OSR Solutions, a consulting/services company started in 2001 that focuses on information management for the life sciences and healthcare industries. For interview feedback, contact Vamsi at vamsi@laxai.com