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Want to know about the latest research findings and hottest jobs in the Pharmaceutical and Biotechnology Industry? Then you’ve come to the right place. When you want up-to-the-minute information and job listings for Clinical Research Associates, Contract Clinical Research Associates and Clinical Trial Managers, Sterling-Hoffman Life Sciences Journal is the source to turn to.
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By Mark R. Kelly, Ph.D., Associate Director of Basic Science Research, IUSCC
 Research that translates from bench to bedside is the hallmark of National Cancer Institute-designated centers, such as the Indiana University Melvin and Bren Simon Cancer Center (IUSCC) in Indianapolis. However, even the NCI recognizes that inefficiencies inherent in academic research translation stall concept-to-care translation. In 2006, leadership at the IUSCC unveiled ITRAC©, a system of mapping successful translational pathways to achieve timely, as well as life saving and enhancing results for cancer patients. Early results suggest that it’s working.
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By Jingfang Ju, Ph.D., Head, Cancer Genomics Laboratory Mitchell Cancer Institute, University of South Alabama
 Human disease is quite complex. In the case of cancer, it is not a single genetic disease but, rather, hundreds of diseases consisting of various combinations of genetic alterations. However, through the development of genomics, personalized medicine can become a reality in the new millennium. The impact of genomics on drug target discovery, drug development, and biomarker-based therapy tailored to an individual’s unique genetic background will be enormous, allowing everyone to benefit from it.
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By Y. John Shyu, Kazuhito Akasaka and Chang-Deng Hu, Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmaceutical Sciences & the Purdue Cancer Center, Purdue University
 Protein-protein interactions are essential for cellular processes. Targeting protein-protein interactions for drug discovery has been challenging due to the lack of sensitive high-throughput screening systems in living cells. Bimolecular fluorescence complementation (BiFC) assay represents one of the most advanced assays for visualization and identification of protein-protein interactions in living cells. We anticipate that the BiFC assay will reinvigorate the interest of the pharmaceutical industry in search for small molecule inhibitors of protein-protein interactions in the near future.
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